Evidence based practice in palliative care is a way to scrutinize the available proof, appraise its quality, and estimate its pertinence to a selected patient before discussing available treatment choices. This approach is utilizing Evidence-based practice (EBP) as an establishment. Evidence-based medicine (EBM) is judicious use of current best evidence in creating choices concerning the care of individual patients. Evidence-based medicine has rapidly developed over the past 20 years. Evidence primarily based on Nursing may be a procedure established on the build-up, translation, examination, and combination of legitimate, clinically important, and relevant analysis. The future of EBM in palliative care must be as various because the patients World Health Organization ultimately derive benefit.